Volumetric capnography and chronic obstructive pulmonary disease staging
نویسندگان
چکیده
Spirometry is difficult for some COPD patient to perform. Volumetric capnography could be a second choice test to evaluate the severity of functional disturbances. The aim of this work is to test this hypothesis. A total number of 98 subjects were classified either as normal ex-smokers (N=14) or COPD patients. The latter were staged following GOLD recommendations. Spirometry and volumetric capnography recordings were obtained from each patient. Spirometry parameters, Bohr Dead Space (V(D)Bohr), Airways Dead Space from the pre-interface expirate corrected curve (V(D)aw), Phase III slope (Sl(III)) and Volume of alveolar ejection (V(AE)) were measured. Index of Ventilatory Efficiency (IVE), and Index of Airways Heterogeneity (IAH) were calculated as: IVE = V(AE)/(V(T) - V(D)aw) and IAH = 1-[(V(T)-V(D)Bohr)/(V(T) - V(D)aw)]. In ANOCOVA analysis IAH showed the greatest association with stage (F >40), with no significant covariant dependence on V(T). A receiver operating characteristics curve analysis showed values of the area under the curve greater than 0.9 for IAH and IVE at all stage levels, with a sensitivity = specificity value greater than 80%. We conclude that IAH and IVE can be used when spirometry cannot be reliably performed, as an alternative test to evaluate the degree of functional involvement in COPD patients.
منابع مشابه
Volumetric capnography as a noninvasive diagnostic procedure in acute pulmonary thromboembolism.
Pulmonary thromboembolism is a common condition. Its diagnosis usually requires pulmonary scintigraphy, computed angiotomography, pulmonary arteriography and, in order to rule out other diagnoses, the measurement of D-dimer levels. Due to the fact that these diagnostic methods are not available in most Brazilian hospitals, the validation of other diagnostic techniques is of fundamental importan...
متن کاملVolumetric capnography as a noninvasive diagnostic procedure in acute pulmonary thromboembolism* Capnografia volumétrica como auxílio diagnóstico não-invasivo no tromboembolismo pulmonar agudo
Pulmonary thromboembolism is a common condition. Its diagnosis usually requires pulmonary scintigraphy, computed angiotomography, pulmonary arteriography and, in order to rule out other diagnoses, the measurement of D-dimer levels. Due to the fact that these diagnostic methods are not available in most Brazilian hospitals, the validation of other diagnostic techniques is of fundamental importan...
متن کاملبررسی همبستگی و میزان توافق نتایج PaCO2 گازهای خون شریانی با CO2 انتهای بازدمی (End-Tidal CO2) توسط کاپنوگرافی در بیماران مبتلا به تشدید حاد بیماری انسدادی ریوی (COPD)
Background : Chronic Obstructive Pulmonary Disease (COPD) represents a major public health problem. The course of COPD is characterized by episodic periods of worsening symptoms, termed exacerbations. Supplemental oxygen should be given to patients with COPD exacerbation without causing CO2 retention. Arterial blood gas sampling is the gold standard for monitoring adequate oxygenation and for...
متن کاملVolumetric capnography for the evaluation of chronic airways diseases
BACKGROUND Obstructive lung diseases of different etiologies present with progressive peripheral airway involvement. The peripheral airways, known as the silent lung zone, are not adequately evaluated with conventional function tests. The principle of gas washout has been used to detect pulmonary ventilation inhomogeneity and to estimate the location of the underlying disease process. Volumetri...
متن کاملCardiopulmonary Mortalities and Chronic Obstructive Pulmonary Disease Attributed to Ozone Air Pollution
Background & Aims of the Study: Ozone is a summer pollutant which can cause respiratory complications, eye burning sensation and failure of immune defense against infectious diseases. Ahvaz city (southwestern Iran) is one of the seven polluted Iranian metropolises. In this study we examined the health impacts of ozone pollution in Ahvaz city during years 2010 and 2011. Ma...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- International Journal of Chronic Obstructive Pulmonary Disease
دوره 2 شماره
صفحات -
تاریخ انتشار 2007